US President-elect Joe Biden delivers remarks on the public health and economic crises at The Queen theater in Wilmington, Delaware on January 14, 2021. - President-elect Joe Biden will propose injecting $1.9 trillion into the US economy when he takes office next week, as evidence mounts that the recovery from the sharp downturn caused by Covid-19 is flagging. (Photo by JIM WATSON / AFP) (Photo by JIM WATSON/AFP via Getty Images)

No one said being the President of the United States was going to be simple, and that is a tough lesson being learned by current President Joe Biden.

In the face of mounting opposition to his pick to lead the Office of Management and Budget, Neera Tanden, being opposed by Democrat Sen. Joe Manchin the president believed he could turn to the tried and true RINO (Republican In Name Only) senators to get her passed.

But two of those RINOS, Maine Sen. Susan Collins and Utah Sen. Mitt Romney, have joined Manchin and other Republicans in saying that they would oppose her, CNN reported.

In a statement, Sen. Collins said that Tanden’s “past actions” showed her animosity and said that the nominee does not have the “experience nor the temperament” to hold the position.

“Congress has to be able to trust the OMB director to make countless decisions in an impartial manner, carrying out the letter of the law and congressional intent,” Sen. Collins said in a statement. “Neera Tanden has neither the experience nor the temperament to lead this critical agency. Her past actions have demonstrated exactly the kind of animosity that President Biden has pledged to transcend.”

As for Sen. Romney, a spokeswoman for the Utah senator said that he cannot support her nomination due to her divisiveness.

“Senator Romney has been critical of extreme rhetoric from prior nominees, and this is consistent with that position. He believes it’s hard to return to comity and respect with a nominee who has issued a thousand mean tweets,” his press secretary Arielle Mueller said.

Last week Sen. Manchin said he would not support her nomination because of past statements she has made about Republican senators and Sen. Bernie Sanders.

“I have carefully reviewed Neera Tanden’s public statements and tweets that were personally directed towards my colleagues on both sides of the aisle from Senator Sanders to Senator McConnell and others. I believe her overtly partisan statements will have a toxic and detrimental impact on the important working relationship between members of Congress and the next director of the Office of Management and Budget,” the West Virginia senator said. “For this reason, I cannot support her nomination.”

Louisiana Republican Sen. John Kennedy earlier this month quipped that Tanden’s tweets called Sen. Bernie Sanders “everything but an ignorant slut.

“I’m very disturbed about your personal comments about people. It’s not just one or two, I think you deleted a thousand tweets. And it wasn’t just about Republicans,” he said. “I mean, you called Sen. Sanders everything but an ignorant slut.”

“I feel terribly,” Tanden said about the attack tweets “I must have meant them, but I really regret them.”

“I want the record to reflect that I did not call Sen. Sanders an ignorant slut,” Kennedy said.

When Sen. Sanders began the hearings, he noted that Tanden had been vicious to both Republicans and Democrats.

“Your attacks were not just made against Republicans. There were vicious attacks made against progressives, people who I have worked with,” he said.

“We need serious work on serious issues and not personal attacks on anybody, whether they’re on the left or the right,” the senator said.

On Monday, White House Press Secretary Jen Psaki reiterated support for Tanden, even as her nomination is crumbling.

“Neera Tanden is an accomplished policy expert would be 1st Asian American woman to lead OMB, has lived experience having benefitted from a number of federal programs as a kid, looking ahead to the committee votes this week and continuing to work toward her confirmation,” she said.